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Chromatin looping-based CRlSPR screen identifies TLK2 as chromatin loop formation regulator in cancer stemness plasticity

DOI: 10.1038/s41467-025-64066-x
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A genome-wide CRISPR/Cas9 knockout screen identifies TMEM239 as an important host factor in facilitating African swine fever virus entry into early endosomes

DOI: 10.1371/journal.ppat.1012256
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A comprehensive benchmark for multiple highly efficient base editors with broad targeting scope

DOI: 10.1101/2024.12.17.628899
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A RT-ERA-CRISPR/Cas12a assay for rapid point-of-care duck hepatitis A virus detection

DOI: 10.1016/j.psj.2025.105316
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Cheng H, Su Y, et al.The ubiquitin ligase KLHL6 drives resistance to CD8+ T cell dysfunction. Nature. 2026 Jan 14. doi: 10.1038/s41586-025-09926-8. Epub ahead of print. PMID: 41535474.

DOI: 10.1038/s41586-025-09926-8
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Gu C, Babujee L, et al. Development of broadly protective influenza B vaccines. NPJ Vaccines. 2025 Jan 7;10(1):2.

DOI: 10.1038/s41541-024-01058-w
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Zhao Wang et al. Multidimensional mapping of stimulation-responsive regulatory elements and candidate causal variants in T cell activation.

doi: 10.1126/sciadv.ady2539
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Hongcheng Cheng et al. The ubiquitin ligase KLHL6 drives resistance to CD8+ T cell dysfunction.

doi: 10.1038/s41586-025-09926-8
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Zifeng Wang et al. Chromatin looping-based CRISPR screen identifies TLK2 as chromatin loop formation regulator in cancer stemness plasticity.

doi: 10.1038/s41467-025-64066-x
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Zheng Sun et al. SMARCA4 Inhibits Breast Cancer Progression and Metastasis through RHOA Suppression.

doi: 10.1158/0008-5472.CAN-24-2801
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Xuran Niu et al. Prime editor-based high-throughput screening reveals functional synonymous mutations in human cells.

doi: 10.1038/s41587-025-02710-z
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Binfeng Liu et al. PKMYT1 kinase ameliorates cisplatin sensitivity in osteosarcoma.

doi: 10.1038/s41392-025-02250-7